| 1976 | Art, Charles, Aaron, and Cyril Neville united to record 'The Wild Tchoupitoulas' alongside their uncle Big Chief Jolly of the Mardi Gras Indian tribe, igniting the idea of the brothers performing together permanently. |
| 1978 | Released their self-titled debut album on Capitol Records, establishing the group as a vehicle for New Orleans' full spectrum of R&B, funk, and Creole soul. |
| 1981 | 'Fiyo on the Bayou' deepened the band's New Orleans identity with a set that drew on second-line rhythms, jazz, and soul rooted in the family's Crescent City heritage. |
| 1987 | Recorded 'Uptown' for EMI with guest appearances by Branford Marsalis, Keith Richards, and Carlos Santana, putting the brothers in conversation with rock and jazz royalty. |
| 1989 | Daniel Lanois produced 'Yellow Moon' for A&M Records, blending the band's soulful grooves with ambient atmospherics and covering Sam Cooke's "A Change Is Gonna Come." |
| 1989 | "Healing Chant" from 'Yellow Moon' won the Grammy Award for Best Pop Instrumental Performance at the 32nd Annual Grammy Awards, showcasing Charles Neville's saxophone. |
| 1992 | 'Family Groove' continued the band's studio run, adding funk-forward production while the brothers remained fixtures at the New Orleans Jazz and Heritage Festival. |
| 2004 | Returned after years off the studio calendar with 'Walkin' in the Shadow of Life' on Back Porch Records, the group's final studio album. |
| 2012 | Gave their farewell concert at the Hollywood Bowl, formally closing the chapter on the group's four-decade run together. |
| 2018 | Charles Neville, saxophonist and a founding voice of the group, passed away, followed the next year by keyboard anchor and co-founder Art Neville, ending any prospect of a reunion. |