Old Crow Medicine Show got its' start busking on street corners in New York state and Canada. They eventually found themselves in Boone, North Carolina, where they caught the attention of folk icon Doc Watson while playing in front of a pharmacy. He immediately invited the band to play at his MerleFest. Shortly thereafter, the band relocated to Nashville for a residency at the Grand Ole Opry, where they entertained the crowd between shows. The band has gone on to tour the world and sell hundreds of thousands of albums. In November of 2011, Old Crow's classic single, "Wagon Wheel," received the RIAA's Gold certification for selling over 500,000 copies. In 2011, Old Crow found themselves embarking on the historic Railroad Revival Tour with Mumford and Sons and Edward Sharpe and the Magnetic Zeros. This tour had the bands riding a vintage train from California to New Orleans, playing shows along the way. More recently, they released the album 50 Years of Blonde on Blonde in 2017. They continue to tour the country by rail and otherwise.