| 1954 | Debuted on stage at the Apollo Theatre in Harlem alongside godmother Dinah Washington at age four, launching a performance relationship with the legendary singer. |
| 1969 | Scored her first R&B hit with "Family Tree," establishing herself as a New York session force while recording commercial jingles for brands including McDonald's, Burger King, and Meow Mix, earning the nickname 'Queen of the Jingles.' |
| 1980 | Contributed lead vocals to godfather Quincy Jones's Grammy-winning album 'The Dude,' cementing a two-decade creative partnership that also produced 'Stuff Like That' and 'From Q With Love.' |
| 1981 | "Baby, Come to Me," her duet with James Ingram from the album 'Every Home Should Have One,' climbed to No. 1 on the Billboard Hot 100, making it one of the biggest pop hits of the decade. |
| 1985 | Collaborated with production duo Jam & Lewis to craft the big R&B hit "The Heat of Heat," broadening her reach beyond pop into club-driven R&B. |
| 2002 | Released 'For Ella,' a Grammy-nominated tribute to Ella Fitzgerald that showcased her jazz artistry and set the stage for a decade of Fitzgerald-focused work. |
| 2007 | Won the Grammy Award for Best Jazz Vocal Album for 'Avant Gershwin,' recorded live with the WDR Big Band in Germany and a Top 5 hit on the Billboard Jazz Chart. |
| 2011 | Released 'Sound Advice' on Shanachie Entertainment, her 18th album, co-producing with Greg Phillinganes and drawing from Bob Dylan, Bill Withers, and original compositions. |
| 2017 | Returned to the Fitzgerald catalogue with 'Ella: Now & Then,' marking the centennial of the jazz icon's birth with a touring program celebrated across Europe, America, and the Far East. |
| 2024 | Received the SFJAZZ Lifetime Achievement Award at the SFJAZZ Gala in San Francisco, honored alongside incoming Executive Artistic Director Terence Blanchard in a ceremony that raised $1.7 million for jazz education. |